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Literature summary for 3.4.21.68 extracted from
- Oviduct-specific expression of tissue plasminogen activator in laying hens (2011), Genet. Mol. Biol., 34, 231-236.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| construction of an oviduct-specific vector containing tissue plasminogen activator protein and green fluorescent protein (pL-2.8OVtPAGFP), and expression in vitro and in vivo in hen eggs, and in oviduct epithelial and 3T3 cells, compared to control vector pEGP-N1. The oviduct-specific vector pL-2.8OVtPAGFP is expressed only in oviduct epithelial cells, no detection in heart, muscle, liver and intestine, whereas pEGP-N1 is detected in oviduct epithelial and 3T3 cells. tPA expressed in egg white and oviduct epithelial cells shows fibrinolytic activity. Subcloning in Escherichia coli | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the fibrinolytic activity of tPA is determined by the fibrin clot lysis assay using fibrin-containing agarose plates | Homo sapiens | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Tissue plasminogen activator | - |
Homo sapiens |
| tPA | - |
Homo sapiens |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
assay at | Homo sapiens |
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Release 2023.1 (January 2023)
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